Ovulation problems

Ovulation induction by Bromocriptine / Cabergoline / Quinagolide

The drugs Bromocriptine, Cabergoline and Quinagolide do not stimulate ovulation by itself, but reduce prolactin secretion. They are prescribed to women who have ovulation problems and are producing excess prolactin. When prolactin levels are normalized, ovulation returns and the chances of pregnancy become normal.

Bromocriptine is given as daily pills; cabergoline and quinagolide are longer acting drugs, more efficient and have fewer side effects compared to bromocriptine. Few patients experience side effects with bromocriptine. The side effects include: nausea, vomiting, dizziness and occasionally blackout. The chance that these symptoms occurring can be reduced by starting the drug a a small dose and gradually build up to a maintenance dose. Prolactin levels need to be checked to confirm that they have been brought down to normal.   Neither ovarian hyperstimulation syndrome nor an increased risk of multiple pregnancy is a side effect of these drugs.

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