What is Intrauterine insemination (IUI)?
The intrauterine insemination (IUI) procedure is the most commonly used method of artificial insemination husband (AIH). It is a relatively simpler and cheaper than in-vitro fertilization (IVF). Intrauterine insemination (IUI) is effective treatment for selected groups of patients. Careful selection of patients for IUI is the cornerstone for achieving good success rates.
Intrauterine insemination has a higher success rates than intravaginal insemination or intra-cervical insemination because it places the good motile sperm near the Fallopian tubes and if combined with ovarian stimulation, then there will be usually more than an egg available for insemination and fertilization. Some couples who have religious or moral objection to IVF find intrauterine insemination acceptable.
Who might benefit from Intra Uterine Insemination?
- Men who are unable to ejaculate inside their wife’s vagina for whatever reasons. Causes for ejaculation failure include diabetes, multiple sclerosis, spinal cord injury and retrograde ejaculation, where sperm are released backward into the bladder instead of urethra. Retrograde ejaculation may be due to diabetes, trauma or operation in the bladder neck or a side effect of certain drugs.
- Men with mildly low, poor quality sperm such as sperm aren't strong enough to swim through the cervix and up into the fallopian tubes or antisperm antibodies.
- women who have minimal or mild endometriosis.
- women with cervical mucus hostility with "unreceptive cervical mucus" (where the mucus surrounding the cervix is hostile to sperm and prevents sperm from getting into the uterus and fallopian tubes)
- Some infertility clinics may offer intrauterine insemination of a HIV negative woman with washed and prepared sperm of her HIV positive husband/partner.
- Women without a male partner, such as women in same-sex partnerships or single women where donor sperm is used.
- Unexplained infertility
The intrauterine insemination (IUI) procedure
The intrauterine insemination procedure involves direct placing of washed and prepared sperm inside the cavity of the womb around the time of ovulation (spontaneous or induced).The use of fresh sperm is associated with higher conception rates than thawed sperm.