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Intra-cytoplasmic sperm injection (ICSI)

The treatment outcomes for intracytoplasmic sperm injection (ICSI) procedures.

Treatment outcome

How successful is ICSI treatment?

ICSI has now been in use for over 11 years and there are over 26,000 babies already born as a result of ICSI worldwide. Fertilization rates are in the region of 60-70% of the injected eggs and cleavage rates of about 80% are expected after ICSI. The risk of complete failure of fertilization is less than 5%. The overall live birth rate per embryo transfer is about 23.1% (HFEA 2000) and 28.7% (SART 2002). This represents an increases of 1-2% compared with last years results. There is wide variability in results between centres. The success rates of ICSI treatment are dependent on the skill and experience of the practitioners. Other factors, which also affect ICSI success rates, include the woman's age, duration of infertility and the number of embryos transferred.

ICSI does not increase the incidence of multiple pregnancy as compared to standard IVF.

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