Risks and complications of IVF treatment

The risk of ovarian and breast cancer

There has been a suggested link between the use of fertility drugs and the risk of ovarian, breast and endometrial cancer. Current studies have suggested the following with regards to each respective cancer:

Ovarian cancer

There are controversial studies linking ovarian stimulation drugs to ovarian cancer. The evidence is observational and there are significant problems in many of these studies, particularly in subgroup analysis, and by inability to control for other cancer confounding factors. Some studies have shown that infertile women who use infertility drugs but still never achieve pregnancy had a significantly increased risk of ovarian cancer compared to women who had no infertility problem.

Sources: Rossing et al. 1991, 2004; Shushen et al. 1996; Gaathier et al. 2004; Kashvap et al. 2004; Brinton et al. 2005

Breast cancer

There appears to be no significant increased risk of breast cancer with fertility drugs.

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