I’m sorry to crash your thread but I have a question I am hoping someone can answer. Long story short-After IVF #5 and another miscarriage, my RE suspects egg quality issues. He thought this before we started and so we did PGD. However, we had 4 of 12 come back as normal and transferred 3. He said that I am only the second patient that has done PDG that has come back with more than 3 (it is only done on select patients). That being said, I met with him yesterday as a follow up and he still thinks egg quality is at play. He said PGD only tests for 10 of the chromosomes and it could even be something other than a chromosome issue. He also said that given my age, 50-60% should have come back normal. His recommendation was donor eggs (DH has no sperm issues).
DH and I had already decided on adoption but you know how life can be, after adoption we may end up back on the IVF wagon with DE. It occurred to me as I was driving away from his office that I forgot to ask an important question.
What causes a 34 year old person to have egg issues? I realize the older people get that their egg quality goes down but that is the only reason I know about. Is there anything a person can do to improve their egg quality? I have always been a great responder, somewhere around 56 eggs with 4 fresh cycles and we have 2 frosties. I’m just trying to put the pieces together and hope someone can help. Thanks!
From what you've posted, I'm not sure you have serious egg issues and I tend to doubt you need a donor. But clinics tend to blame the embryos. They transfer some embryos that look good and nothing happens. Must be the embryos, right? Wrong.
Jerome Check ran some interesting studies years ago. He has long had this "free IVF" program for patients who have good response and are willing to share their eggs as egg donors, while keeping some for themselves. He quickly noticed that the recipients of the donated eggs got pregnant much more often than those donors who got their own eggs. Now, since these were splits from the same sets of eggs, there was no way to blame the eggs. Turns out ovarian stimulation impairs endometrial receptivity. That's why the donors using their own eggs had more failures, because they just underwent stimulation. The donor recipients did not.
It seems a non-receptive endometrium is a major cause of IVF cycle failure. Yes, using an egg donor will fix endometrial receptivity issues, but not primarily because of the eggs. It's because of the lack of ovarian stimulation in the female receiving the transferred embryos in a donor cycle.
Of course, there are some women who cannot produce eggs, almost always over 40 years old, and obviously these women need egg donors.
Keep in mind that, in the US, most clinics report their data to SART and all are required to report to the CDC (usually through SART). The reports from SART and the CDC reflect the percentage of cycles that result in live birth. Accepting patients with prior failures, who are now a little more likely to fail, will decrease the live birth rates and make the clinic look bad. Hence there is some pressure to divert patients into donor IVF more often than necessary.
I don't know what clinic you are using, and I am speaking only very generally.
Avoid IVF and surrogacy in Ukraine. Ukrainian centers pay shills to post here under numerous sock accounts pretending to be patients in Ukraine. Centers using such deceptive advertising cannot be trusted and should be avoided.