Post
by children » Tue Oct 21, 2008 6:18 am
Hi Tammy,
I am very happy for you and your dh! Here is the protocol that worked twice nicely for me.
1) BCP: for 21 days (starts from the 2nd or 3rd day of ur period)
2) Lupron: for 14 days, 20U/day, starts at the 17th day of BCP overlapping with the last 5 days of BCP)
3) E2 dots (Patches, 0.1 mg/dot): starts on the 10th day of Lupron use which overlaps with the last 5 days of Lupron.
The dose is increased progressively: 1 dot for 4 days (change to new dot every 2 days), 3 dots for 4 days (change to new ones every 2 days), then 4 dots for the rest of journey (change to new ones every 3 days). Keep at this level until your blood E2 level reaches above 200 and lining reaches 8 mm (for me, it took 15 days after the start of E2, but my E2 level was boosted by the use of estrace pills since my level was not hi enough). Continue this until pg test. If positive, continue until 10th week pg.
4) Progesterone: starts at 20th days of the E2. Every Morning, 50 mg/ml, injection (PIO), before bed: 100 mg/suppository. Keep at this level until pg test, if positive, continue until 11th week.
5) Transfer day: generally is 24th day after the start of E2.
6) After transfer, continue E2 dots and progesterone until pg test.
My embryo thawing survival rate were: 5/6, 6/8 and 5/5, respectively. All embryos were frozen at 2-cell stage and they were all from the same batch.
Yes, REs only can tell you statistics, but we had 10% and others had higher. As I mentioned before, one of my friends had twins with 3 embryos of hers transferred at 43. One never knows who will be the lucky one, we can only try our best but prepare for the worst.
Let's hope that ur all 4 eggs survive and will be fertilized nicely! Good luck on your next try!
Hi Caroline,
I see ur dilemma and I had the same issues as yours. But my REs know that I am a good responder to ivf drugs, plus "pg to a live birth" history, they agreed to give me another fresh ivf, if my last frozen cycle didn't work.
Since u are also a good responder and had a live birth, can u talk them into another fresh cycle? If not, I just had a crazy idea: ask ur doc to prescribe progesterone to u so that you can use it every cycle after ovulation. I honestly think that we older women cannot keep a viable pg is due to low natural P4 levels, as much as the "bad egg quality". I had several positive pg tests after DD was born, but none of them lasted more than 5 weeks. Although not confirmed by blood pg tests, I believe they were real positives that I could not keep due to the fact that no progesterone was supplemented.
Similar to u, I enjoy every moment w our DD and I often feel bad about my ongoing pg since I did almost nothing to show my love for him. I sometimes ask my dh whether we can really love our future son as much as we love our dd, he gives me very vague answers. I don't have a clear answer for why I wanted more than 1 child, and I also don't know how many children for us is appropriate. I had not had time to sort out these questions before trying for the second...
I will let you all know how it will be once our son is born...
Catharine,
How are u doing? My belly is huge now, although I have not much troubles to move around.
Rhonda,
I saw Tammy answered ur Qs, welcome more of them, we all have a lot to learn. Good luck on your coming cycle and please keep us updated!
Everyone else here, take care!
Yasmina
Me, 50 DH, 40
IVF, 11/05, 19 embryos(e), no ET, OHSS
FET, 02/06, cancelled, dominant egg
FET, 04/06, 4e, BFN
FET, 06/06, 6e, DD born 02/07
FET, 05/08, 5e, DS born 01/09
http://yasminachina.blogspot.com/