Poor Ghost! I have another question..

Discussion group for all topics related to infertility including preparation for pregnancy, causes, investigation and treatment of infertility.
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Corinna
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Posts: 100
Joined: Thu Mar 30, 2006 8:42 am
Location: Manchester

Poor Ghost! I have another question..

Post by Corinna » Tue Aug 01, 2006 12:18 pm

Hey Ghost!! :D

I hope your well. I'm really sorry to bother you again, but I was just wondering whether you could shed some light for me.

I have my review consultation booked in at my clinic in 2 weeks. I had a BFN last month and I have 3 frozen embies which I am going to use in Oct.

When I had my fresh transfer last month, they transfered 2 grade 1's (a 2 cell & a 4 cell). I had my transfer at 10am and the embryologist called me later that afternoon to tell me that I had 3 embies that were suitable for freezing.

My question is: Would the 3 embies that they froze likely to have divided further before freezing?? Do most clinics let them divide further before freezing? I am worried that they froze the 3 embies when they were at 2 or 3 cell stage. Its likely that they will lose some cells when they are thawed. I think the liklihood of getting a BFP from a 1 or 2 cell frozen embie is quite slim. I could be wrong.. :?

What are your thoughts??

Many thanks Ghost. Your a superstar!! :)
Me31.DH39.DD14 (natural conception with college BF)
No tubes (2 Ectopics in 2000 with ex)
DH non obstructive azoospermia.
ICSI July 06-BFN
FET Sept 06-BFN
ICSI with donor sperm Aug 07-BF?????

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Ghost
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Joined: Mon May 29, 2006 5:01 pm

Post by Ghost » Tue Aug 01, 2006 1:58 pm

A clinic can transfer fresh on one day (say, day 2 or 3) and then culture embryos to a more advanced stage (say, blastocyst) before selecting embryos for freezing. I don't know any that do this routinely, however.

Since the embryologist called you the same day as the transfer to inform you about embryos for freezing, it seems likely that those frozen embryos were frozen at the same stage (same day) as those that were transferred. Your clinic will know for sure if he froze that day or perhaps a little later. Ask them.

I think you have a valid concern. Check your clinic's success rates with frozen embryos. I'd still recommend using those frozen embryos rather than going through stimulation again, but the statistics will give you a rough idea of your chances.

Corinna
Regular
Posts: 100
Joined: Thu Mar 30, 2006 8:42 am
Location: Manchester

Post by Corinna » Tue Aug 01, 2006 3:48 pm

Ghost.

You've been as helpful as always!! :D

I've just checked on my clinics website. Live birth rates per embryo transfer for a fresh cycle is 38%. The live birth rate per embryo transfer for a frozen embie is 28%. This seems okay to me?? Whadda you think??

Also, one last question then I will leave you in peace.. :) Would you recommend that I ask my clinic to leave my frozen embies for 1 day after thawing and before transfer to see how they get on or would you recommend that I have them transfered straight away irrespective of how many cells they have??

Many thanks.

Phew!! I'm going for a brandy!! :wink:
Me31.DH39.DD14 (natural conception with college BF)
No tubes (2 Ectopics in 2000 with ex)
DH non obstructive azoospermia.
ICSI July 06-BFN
FET Sept 06-BFN
ICSI with donor sperm Aug 07-BF?????

Ghost
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Posts: 4150
Joined: Mon May 29, 2006 5:01 pm

Post by Ghost » Tue Aug 01, 2006 7:30 pm

Corinna wrote:I've just checked on my clinics website. Live birth rates per embryo transfer for a fresh cycle is 38%. The live birth rate per embryo transfer for a frozen embie is 28%. This seems okay to me?? Whadda you think?
Those are pretty typical numbers. If it was me, I'd go for the FET cycle, no question about it.
Also, one last question then I will leave you in peace.. :) Would you recommend that I ask my clinic to leave my frozen embies for 1 day after thawing and before transfer to see how they get on or would you recommend that I have them transfered straight away irrespective of how many cells they have?
That is a great idea, and it makes sense scientifically ( :wink: ) , however I'd probably just let them do whatever their current best practice is. Don't want them trying something new on you. If what you suggest is routine for them, then go for it. Otherwise stay in their comfort zone.

If they are willing to do the additional culturing post-thaw, I'll have some questions for you about how they proceed with it.

kristin
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Joined: Tue Apr 11, 2006 7:35 pm
Location: london

Post by kristin » Thu Aug 03, 2006 1:04 pm

dear Ghost

was wondering if I could post an additional question here.... how long can frozen embies be frozen for? I have a few in storage and am curious as to how long they can keep!

many thanks
Kristin
me 36, dh 47
ttc 2 years
May 06: ivf + icsi: BFP- little gal born feb 07

Ghost
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Post by Ghost » Fri Aug 04, 2006 12:30 am

kristin wrote:dear Ghost

was wondering if I could post an additional question here.... how long can frozen embies be frozen for? I have a few in storage and am curious as to how long they can keep!

many thanks
Kristin
I don't believe anybody knows the limit. There are reports of success after more than 10 years.

An issue you might consider is the probability of equipment malfunction over a long period of time, with Murphy's law and all.

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