No "down-regulation"? Please help? Ghost?

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DandMe
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No "down-regulation"? Please help? Ghost?

Post by DandMe » Sun Jan 03, 2010 11:17 pm

Hi there... I hope someone can help.

When I first got to my clinic they said I was to do a round of Follistim but after my tests were reviewed and DH's 'availability' was considered, they are keeping me on BCP until January 12th, then baseline on January 15th and stims Bravelle and Menopur (sp?) on the 15th.

Am I missing something by skipping the Follistim before we start the stims? Are my chances lowered?
Sonya, 40 - DS, 24 DS, 22
David, 45
unexplained
2008 BFP, 2010 IVF & FET MC
2010 IVF #2 - BFP
14dpo 138
16dpo 351
Perfect pregnancy/Delivery July 2011
FET #2 June 2012
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poohgirl
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Post by poohgirl » Thu Jan 14, 2010 9:02 pm

I think I might be missing something, follistim is the drug to make you grow follicles not to down reg. I used Lupron to down reg is that what you mean?
[img]http://lbdf.lilypie.com/1LNqm6.png[/img][
me 36 Husband 40
8 IUI's all BFN's
1st IVF March 08 BFN
1st FET June 08 BFP!!! m/c October 08
2nd IVF Jan 09 cancelled
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Oct 09 BFP Beta 11dp5dt 1149.8!

Ghost
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Re: No "down-regulation"? Please help? Ghost?

Post by Ghost » Thu Jan 14, 2010 9:37 pm

DandMe wrote:Hi there... I hope someone can help.

When I first got to my clinic they said I was to do a round of Follistim but after my tests were reviewed and DH's 'availability' was considered, they are keeping me on BCP until January 12th, then baseline on January 15th and stims Bravelle and Menopur (sp?) on the 15th.

Am I missing something by skipping the Follistim before we start the stims? Are my chances lowered?
Bravelle, Menopur, and Follistim (and Gonal F and Repronex) all do the same thing. They are FSH products for stimming follicles. You can stim with any one or more of them.

You probably refer to Lupron for down-regulation. Lupron is used to prevent a premature LH surge.

Your doctor almost certainly has another drug in mind for you, probably ganirelix acetate, for that same purpose. With a GnRH antagonist like ganirelix, you don't need to start it until the LH surge threatens, around the 5th day of stim or so. It directly suppresses the pituitary immediately.

With a GnRH agonist like Lupron (agonist is the opposite of antagonist), you must start many days in advance because it initially causes an LH surge, then continued use prevents an LH surge by keeping the pituitary depleted or desensitized.

The two families of drugs achieve the same end result in opposite ways.
Avoid IVF and surrogacy in Ukraine. Ukrainian centers pay shills to post here under numerous sock accounts pretending to be patients in Ukraine. Centers using such deceptive advertising cannot be trusted and should be avoided.

DandMe
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Joined: Sat Dec 26, 2009 2:25 pm
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Post by DandMe » Fri Jan 15, 2010 6:26 am

I did mean Lupron and yes, that's what my clinic assured me was happening. Thanks so much for the answer, sorry for my mix up on the meds!
Sonya, 40 - DS, 24 DS, 22
David, 45
unexplained
2008 BFP, 2010 IVF & FET MC
2010 IVF #2 - BFP
14dpo 138
16dpo 351
Perfect pregnancy/Delivery July 2011
FET #2 June 2012
ImageImage

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