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Pregnant while on Lupron...so scared

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Pregnant while on Lupron...so scared

Postby misangels3 » Sat Dec 24, 2011 4:09 pm

Anyone else experienced this or know someone who found out they were pregnant while taking Lupron? I went in on cycle day 19 to start my first FET. They start me on Lupron day 21 but they only had openings for appointment on day 19 of my cycle. I had ultrasound, progesterone test, and pregnancy test. Dr. said ultrasound showed no follicles that were mature on day 19 and that I must not have ovulated this cycle. Pregnancy test came back negative and progesterone was really low which he says shows I didn't ovulate this cycle. So he put me on Norethindrone 7 days to speed up process of menstruation and started me on lupron on day 21. I expressed my concerns to Dr. that I usually ovulate later in my cycles and had mentioned that during my prior IVF and he said he would be able to tell if I am pregnant or not by day 21. Soooo....on day 14 of taking Lupron (20 unit daily) I didn't get my period. I called the office they said it is normal so I went in for U/S and blood test for estrogen level and to measure thickness of lining. U/S showed 6mm lining Dr. said lining "ok" and that I had cyst on my Right ovary. Blood test came back high estrogen so they had to run pregnancy test and it came back hcg 278......OMG......Now I am totally scared. I have been on those drugs. They did not tell us to use protection or put me on BCP month prior. AFter my u/s on day 19 I said so now we have to use protection as I am starting LUpron. Nurse says yes from now on use form of birth control. We did, but the day before the u/s on day 19 we had intercourse we were not told not to and we assumed as the Dr. had assured us he would be able to tell if we were pregnant or not before giving lupron. Well the sperm must have been waiting adn I must have ovulated after the u/s within 2 days or so. They said my hcg puts me at 4 weeks along which would mean I ovulated that same day that the ultrasound was done. Also the cyst they saw was the corpus luteum on my right ovary supplying pregnancy. Weird cause they found my tube is blocked on the right side. I have severe endo and my husband low sperm motility. TTC 2.5 yrs with miscarriages. Help....please....I have read all literature on Lupron birth defects or lack of literature on lupron and pregnancy obviously...
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Re: Pregnant while on Lupron...so scared

Postby Ghost » Sat Dec 24, 2011 5:49 pm

misangels3 wrote:Anyone else experienced this or know someone who found out they were pregnant while taking Lupron? I went in on cycle day 19 to start my first FET. They start me on Lupron day 21 but they only had openings for appointment on day 19 of my cycle. I had ultrasound, progesterone test, and pregnancy test. Dr. said ultrasound showed no follicles that were mature on day 19 and that I must not have ovulated this cycle. Pregnancy test came back negative and progesterone was really low which he says shows I didn't ovulate this cycle. So he put me on Norethindrone 7 days to speed up process of menstruation and started me on lupron on day 21. I expressed my concerns to Dr. that I usually ovulate later in my cycles and had mentioned that during my prior IVF and he said he would be able to tell if I am pregnant or not by day 21. Soooo....on day 14 of taking Lupron (20 unit daily) I didn't get my period. I called the office they said it is normal so I went in for U/S and blood test for estrogen level and to measure thickness of lining. U/S showed 6mm lining Dr. said lining "ok" and that I had cyst on my Right ovary. Blood test came back high estrogen so they had to run pregnancy test and it came back hcg 278......OMG......Now I am totally scared. I have been on those drugs. They did not tell us to use protection or put me on BCP month prior. AFter my u/s on day 19 I said so now we have to use protection as I am starting LUpron. Nurse says yes from now on use form of birth control. We did, but the day before the u/s on day 19 we had intercourse we were not told not to and we assumed as the Dr. had assured us he would be able to tell if we were pregnant or not before giving lupron. Well the sperm must have been waiting adn I must have ovulated after the u/s within 2 days or so. They said my hcg puts me at 4 weeks along which would mean I ovulated that same day that the ultrasound was done. Also the cyst they saw was the corpus luteum on my right ovary supplying pregnancy. Weird cause they found my tube is blocked on the right side. I have severe endo and my husband low sperm motility. TTC 2.5 yrs with miscarriages. Help....please....I have read all literature on Lupron birth defects or lack of literature on lupron and pregnancy obviously...


Well, congratulations!

I recommend you ask your RE and perhaps your Ob/Gyn about this. I suspect you have a perfectly fine little one who beat some amazing odds.
Note: I am not an MD and not an expert.
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Re: Pregnant while on Lupron...so scared

Postby misangels3 » Sun Dec 25, 2011 2:43 pm

Ghost-
Hopefully it would all work out ............however I am thinking it might be ectopic as my tube is "scarred shut" per the Dr. or also it has been on my mind that my uterine lining is dangerously thin so how could it be possible to implant correctly. Also I have recurrent miscarriages so a lot has been on my mind as well as a study I read which said 30% chance of miscarriage in women who got pregnant and were taking lupron. I feel it would be a far stretch to have any sort of a happy ending. I have to wait and see what hcg comes back at on Tuesday.
I could never imagine that my husband and I would have to deal with infertility....and on top of that recurrent miscarriages, and now this. Is there a light at the end of the tunnel?
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Re: Pregnant while on Lupron...so scared

Postby Ghost » Sun Dec 25, 2011 3:58 pm

misangels3 wrote:Ghost-
Hopefully it would all work out ............however I am thinking it might be ectopic as my tube is "scarred shut" per the Dr. or also it has been on my mind that my uterine lining is dangerously thin so how could it be possible to implant correctly. Also I have recurrent miscarriages so a lot has been on my mind as well as a study I read which said 30% chance of miscarriage in women who got pregnant and were taking lupron. I feel it would be a far stretch to have any sort of a happy ending. I have to wait and see what hcg comes back at on Tuesday.
I could never imagine that my husband and I would have to deal with infertility....and on top of that recurrent miscarriages, and now this. Is there a light at the end of the tunnel?


I'm hoping so. The effect of Lupron is through shutting down LH from the pituitary. Your little one is now making hCG, and plenty of it (276!). hCG from the embryo activates the same receptor as pituitary LH, so that LH is no longer relevant. So I'm suspecting your little one pulled off a Christmas miracle. But it takes further tests and ultrasounds to tell.

A 6mm lining can still work. It's just less than ideal.

You are probably smart to not pin a lot of hope on it just yet. These early ones are often lost, even without the issues you've raised. And it might be ectopic. But I would also not give up on it, and I'd get it checked out. You are pregnant, despite all the obstacles.
Note: I am not an MD and not an expert.
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Re: Pregnant while on Lupron...so scared

Postby misangels3 » Tue Dec 27, 2011 6:26 pm

HCG rose from 278 (last thursday) now to 1,960 (today Tuesday). I go in 2 days- Thursday for another hcg check. Cross my fingers. The clinic nurses said they have had a few that got pregnant while on lupron and babies were normal.
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Re: Pregnant while on Lupron...so scared

Postby misangels3 » Fri Dec 30, 2011 2:24 am

now hcg rose to 4,016...now have to wait for ultrasound. Kind of wishing they would do it earlier to rule out ectopic d/t circumstances mentioned above. Ultrasound in 2 weeks Jan 12
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Re: Pregnant while on Lupron...so scared

Postby LYD10 » Fri Dec 30, 2011 2:36 am

Looking good, angels! Keep us posted please onto u/s
ME 40, DH, 43
#1 IVF BFN
#2 FET DS born
#3 IVF ectopic
#4 FET BFN
#5 FET Chemical
#6 IVF, BFP at 8dpo, beta 215, started out with twins, one vanished at 6 weeks, EDD 9/4/12
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Re: Pregnant while on Lupron...so scared

Postby MamaBoo » Fri Dec 30, 2011 6:51 pm

The way your beta is rising, I wouldn't be worried about eptopic. They usually tend to rise much more slowly, and you usually kind of know something isn't quite right because of the way the beta rises.
Me 34 endo, MTHFR, clotting issues
DH 47 semi-low morphology
TTC 6 yrs
3 IUI's all BFN
IVF#1: 10/08 BFP early MC
FET#1: 03/09 BFP
DS born 11/28/09
FET#2: 03/11
DS born 11/21/2011
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Re: Pregnant while on Lupron...so scared

Postby misangels3 » Fri Dec 30, 2011 7:56 pm

thanks LYD10
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