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Puregon + Menopur GHOST

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Puregon + Menopur GHOST

Postby fruit » Sat Oct 06, 2012 1:01 am

Hello Ladies and Ghost,

I've been away for a while but im back, i guess i cant go on in this journey without these boards and the ladies here....

so, my RE has prescribed me puregon and menopur together (everyday) for my new ivf cycle.
im 30 years old and i have no issues (only male factor), i have lots of follicules and my FSH is normal, so i am wondering why did my RE wants to use menopur with the puregon, why puregon is not enough??
through all my previous cycles i always used only puregon for stimulation and i always had lots of good eggs and embryos (but always a BFN)

Ghost do u have any idea about the "puregon + menopur" protocol? and why using both of them?

i know that the difference between the two is that menopur contains FSH AND LH, can u please explain to me in which cases do they use only FSH (puregon) for stimulation and in which cases they uses FSH + LH (menopur) ???

Ps: I have PCO, is it wise to use a medication with LH such the menopur???

thank you,
Last edited by fruit on Sat Oct 06, 2012 1:22 pm, edited 1 time in total.
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Re: Puregon + Menopur GHOST

Postby WeHaveHope » Sat Oct 06, 2012 3:53 am

Fruit-I don't know if you remember me but we cycled together last year. I am so glad you are back. I will be following you and cheering you on when you get your BFP.
Mrd 11y TTC 8y
Me38 DH49
DS14pr mrg
2 step-ch16&20
IUI 12/10 BFN
IVF 1/11 OHSS
FET 5/11 BFN
FET 7/11 MC
FET 9/11 MC46 XY
FET 12-30-11 BFP 15dpo=266,17dpo=727,22dpo=7125,25dpo=19076,1-20 u/s 2HB's. Our 2 little miracles born on 8-15-12@35w/3d
ImageImage
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Re: Puregon + Menopur GHOST

Postby fruit » Sat Oct 06, 2012 12:56 pm

Hello Maria, of course i remember you and all the ladies i cycled with, i couldnt go on without u all..
CONGRATS on ur baby girls! They are absolutely adorable! Im so happy for you :)
Hugs
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Re: Puregon + Menopur GHOST

Postby Ghost » Sat Oct 06, 2012 2:32 pm

fruit wrote:Hello Ladies and Ghost,

I've been away for a while but im back, i guess i cant go on in this journey without these boards and the ladies here....

so, my RE has prescribed me puregon and menopur together (everyday) for my new ivf cycle.
im 30 years old and i have no issues (only male factor), i have lots of follicules and my FSH is normal, so i am wondering why did my RE wants to use menopur with the puregon, why puregon is not enough??
through all my previous cycles i always used only puregon for stimulation and i always had lots of good eggs and embryos (but always a BFN)

Ghost do u have any idea about the "puregon + menopur" protocol? and why using both of them?

i know that the difference between the two is that menopur contains FSH AND LH, can u please explain to me in which cases do they use only FSH (puregon) for stimulation and in which cases they uses FSH + LH (menopur) ???

Ps: I have PCO, is it wise to use a medication with LH such the menopur???

thank you,


Hi Fruit!

Puregon contains FSH only. Yes, you are correct that Menopur contains FSH, LH, and hCG. The hCG and LH give it a little bit of "LH activity", mostly from the hCG. hCG and LH do almost exactly the same things.

Using the two products allows your RE to adjust your LH exposure by adjusting the relative doses of each product.

One theory is that LH promotes estradiol production and therefore reduces progesterone exposure (LH and hCG promote conversion of progesterone into estradiol in the follicles). Too much early progesterone exposure has been associated with reduced chance of pregnancy.

I don't know why a clinic would use only Puregon, but I don't doubt there are some that do.

In a natural cycle, FSH and LH are always provided together from the pituitary.
Note: I am not an MD and not an expert.
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Re: Puregon + Menopur GHOST

Postby fruit » Sat Oct 06, 2012 2:41 pm

Thank you very very much Ghost for your answer!
Dont know what to do without u...
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Re: Puregon + Menopur GHOST

Postby to_have_fun08 » Mon Oct 08, 2012 4:00 pm

Good Luck Fruit!!!
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Re: Puregon + Menopur GHOST

Postby leorira11 » Mon Oct 08, 2012 4:22 pm

I've done cycles on only Puregon and cycles on only Menopur - and gotten pregnant from both kinds. (This pregnancy is from a Puregon only cycle -- and I didn't see much of a difference in results between the two types. I actually asked my doctor for the just Puregon, because I find the pen-injections much easier than having to reconsitute like the Menopur)

Good luck Fruit! Let us know how it goes!
8 IVF+6 FET=6 BFN+8 BFP =

-b/g twins 22w (12.09)
-mc 10w (9.10)
-Micha (7.19-24.11) & Asaf (7.19-28.11) born at 24w
-mc 5wk (2.12)
-no HB at 18w (10.12)
-BO (4.13)-
-mc 6wk (9.13)

last attempt - donor sperm - baby girl born healthy July 2014
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Re: Puregon + Menopur GHOST

Postby Ninde » Mon Oct 08, 2012 8:54 pm

Hi, I actually got pregnant on puragon only. I miscarried at 9 weeks but it happened. I had puragon the second d time and didnt and I had menopur only this time - much better quality embryo but no pregnancy.

Good luck fruit

Ninde
Ivf # 1 aug 2011 bfp. M/C 9 weeks
Ivf # 2 Mar 2012, beta Apr 12: Bfn
Ivf # 3 Aug 2012, another heart breaking bfn
Ivf # 4 Feb 2012
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Re: Puregon + Menopur GHOST

Postby fruit » Tue Oct 09, 2012 12:24 am

Hey Ladies! Thanks a lot for your answers and for wishing me good luck! I truly need it!

To have fun: thank u :) are u pregnant with ur number 2 ??

Leora: Congrats on ur pregnancy :) im so excited for you!

Ninde: thanks a lot, are you going to try again anytime soon?
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Re: Puregon + Menopur GHOST

Postby Ninde » Thu Oct 11, 2012 11:26 pm

Fruit: I think so. We have a second opinion next week and I'll see what they say. How are you feeling?

Ninde
Ivf # 1 aug 2011 bfp. M/C 9 weeks
Ivf # 2 Mar 2012, beta Apr 12: Bfn
Ivf # 3 Aug 2012, another heart breaking bfn
Ivf # 4 Feb 2012
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