What is the nature of the mosaicism? Which chromosomes? Do they suggest trisomy or monosomy?
This is all too new to give out any solid or proven advice. However, I would consider transferring it if the mosaic results do not suggest trisomy in chromosomes 13, 18, or 21, or any aneuploidy in the sex chromosomes. That way, in theory, the worst that can happen is a failure.
Mosaic results are fairly common. Live births of healthy infants have been achieved with some embryos with mosaic results. The data are very sparse, but it seems the chance of live birth with the transfer of a mosaic embryo is perhaps in the 10-30% range.
Richard Scott (a leader in this field) argues that most mosaic results are actually normal embryos. Others argue that abnormal cell lines in the embryo tend to die out, leaving only the normal lines to become the infant (that might apply to most aneuploidies, but not those few I specifically listed above), or maybe the cells we biopsy from the trophectoderm tend to be worse that those in the inner cell mass. Maybe. The inner cell mass, by the way, becomes the infant, and we don't sample those cells.
You raise another important point. At age 40, time can be critically important. Your ovarian reserve can be declining rapidly. That's an even bigger factor if you are hoping to have multiple children.
I hesitate to give advice on what to do, but I have told you generally what I know.
Last edited by Ghost
on Wed Jan 25, 2017 9:07 pm, edited 1 time in total.
Avoid IVF and surrogacy in Ukraine. Ukrainian centers pay shills to post here under numerous sock accounts pretending to be patients in Ukraine. Centers using such deceptive advertising cannot be trusted and should be avoided.