Jovigal wrote:Ghost - just curious but are you male? I've always had early symptoms that are legit.
Yes, I am a male scientist that studies IVF.
But my statement still stands. Cramps are common side effects from progesterone, and cannot indicate pregnancy in IVF cycles. So absence of cramps does not indicate absence of pregnancy. Using cramps as an indicator can give wrong impressions in either direction.
Don't take my word for it. Here's the page on drugs.com that describes the side effects of Crinone, a common progesterone supplement FDA-approved for use in assisted reproduction:
"Other, less serious side effects are more likely to occur, such as:
* mild nausea, vomiting, bloating, stomach cramps..."
There's a long list.
At implantation embryos are smaller than salt grains. You cannot sense them. The tiny amount of hCG they make at that stage also cannot be sensed, unless you are having OHSS. Worsening OHSS is the only sign of pregnancy you can have on the 2WW.
In a natural pregnancy, you might sense the effect of the hCG as it signals the corpus luteum (CL) to continue making progesterone, because you can sense the effects of that progesterone. But in IVF you are getting progesterone anyway, so you can't tell whether that progesterone is coming from a CL stimulated by hCG or from the supplements.
If patients could sense their pregnancies, we would not need the tests.