Lovenox is my next step

Discussion forum for those particularly interested in IVF and embryo transfer including frozen embryo transfer.
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Lifelove
Member
Posts: 58
Joined: Tue Nov 09, 2010 7:33 pm

Lovenox is my next step

Post by Lifelove »

I know there are a lot of women on the boards that have used Lovenox, why did your doctor decide to suggest that? I am wondering why I can't just try baby asprin instead. My RE thinks this is the next step for me, I would start the daily injections on day 1 of a BFP. The unknown scares me, I am worried about major side effects to myself or the fetus.

Can anyone offer any Lovenox advice?

Thank you.
me-33 DH (34)
IVF1 & 2- 5/3/09 & 9/10 - chem
MTHFR - folbee
3- FET (12/17/09) BFP (7 wk m/c)
4- (4/14/10) BFN
5- (10/26/10) 3dt -ectopic
6- BFN
7- BFP - HCG 56.3 2nd 256
8-Fresh cancel
9-FET 11/28/11 BFP
http://www.thoughts.com/LittleStrawberry
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blairwh58
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Posts: 697
Joined: Mon Jun 07, 2010 11:24 am
Location: Kentucky

Re: Lovenox is my next step

Post by blairwh58 »

Lifelove- I actually started Lovenox with the cycle. I have been on baby aspirin for a few months now, but after 3 unsuccessful IUIs, and 2 unsuccessful IVFs they were starting to wonder what was wrong with me. We did tons of bloodworks and even genetic testing and found out that I was homozygous for the MTHFR gene which can cause the blood to clot off once the embryo attaches. So with this FET cycle I started the Lovenox injections 5 days after the transfer. Im not going to lie they actually burn/sting pretty bad, but it only lasts a few minutes. Other than that the only side effect was bruising on my stomach, and some little knots. The only down side is the cost- and the fact that my insurance required a Prior Authorization which was a hassle. Not sure if it was the Lovenox or the other changes we made to this cycle but it looks to be working so far. Best of luck to you all!!
Me- 26y unkn inf.
DH-30y MF
TTC for 3 yrs
2010- 3 IUI, 3 IVFs (1 chemical, 1 MC @ 6wks)
IVF #4- Fresh 5dt w/ 2 blasts & 1 pre-blast.
BFP! Beta 4/15= 667, 4/18= 2244, 4/22=15,181!!!
Triplets turned Twins- lost 1 baby @ 10 wks. 2 Baby Girls!!
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Lifelove
Member
Posts: 58
Joined: Tue Nov 09, 2010 7:33 pm

Re: Lovenox is my next step

Post by Lifelove »

Thank you so much for your reply. I have one of the MTHFR mutations myself so I wonder if that plays a role in all of this. Thanks for putting my mind at ease, I don't mind bruising if that is the worst of the side effects. Glad to hear your cycle is looking good!
me-33 DH (34)
IVF1 & 2- 5/3/09 & 9/10 - chem
MTHFR - folbee
3- FET (12/17/09) BFP (7 wk m/c)
4- (4/14/10) BFN
5- (10/26/10) 3dt -ectopic
6- BFN
7- BFP - HCG 56.3 2nd 256
8-Fresh cancel
9-FET 11/28/11 BFP
http://www.thoughts.com/LittleStrawberry
brit1612
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Posts: 591
Joined: Sun Sep 16, 2007 7:19 pm

Re: Lovenox is my next step

Post by brit1612 »

Lifelove- Our baby boy was born in March with me being on Lovenox. I do not have the clotting disorder, but I had three miscarriages and the doc thought it would be worth a try. I don't know if it helped or not, but we finally have our little boy.

We did have a problem with the lovenox that I want to share with you. Please know that the situation is unique, and I do believe the lovenox helped us to have our little guy. When I went for a high level ultrasound at about 12 weeks, they saw that I had a subchorionic hemorrage (it is a bleed on the placenta). My doc sent me to a high risk doctor and the bleed had already gotten really large. (It was NOT caused by the lovenox) The doctor said that I needed to stop the lovenox immediately because it was making the bleed larger. She thought that I was going to miscarry, but I didn't, I stopped the lovenox and the bleed went down. I'm sure that the situation was rare, and you need to do what your doctor suggest. I am not trying to scare you, I just want you to be aware of the possibilities.
After 7 attempts (2 negatives/3 miscarriages), we have TWO miracle boys!! If you would like to hear our story, please visit http://www.ivfsuccessstories.info. Never give up, it can happen for you!!
Lifelove
Member
Posts: 58
Joined: Tue Nov 09, 2010 7:33 pm

Re: Lovenox is my next step

Post by Lifelove »

Thank you Brit I appreciate the honesty and stories, that is what I am looking for. I am glad to hear you went on to have a little boy. I am mostly nervous about cutting myself since I am a baker/cook I do a lot of chopping and cutting.
me-33 DH (34)
IVF1 & 2- 5/3/09 & 9/10 - chem
MTHFR - folbee
3- FET (12/17/09) BFP (7 wk m/c)
4- (4/14/10) BFN
5- (10/26/10) 3dt -ectopic
6- BFN
7- BFP - HCG 56.3 2nd 256
8-Fresh cancel
9-FET 11/28/11 BFP
http://www.thoughts.com/LittleStrawberry
brit1612
Regular
Posts: 591
Joined: Sun Sep 16, 2007 7:19 pm

Re: Lovenox is my next step

Post by brit1612 »

I don't think you should worry about that. I was on Lovenox twice, (the first time we didn't start it until after I was pregnant and we were afraid I was going to lose it- which we did) and I never had any problems with bleeding. The only time i noticed a difference was when I had the miscarriage. I bled a lot more than I did with the first one. Good luck to you! Hope everything works out!
After 7 attempts (2 negatives/3 miscarriages), we have TWO miracle boys!! If you would like to hear our story, please visit http://www.ivfsuccessstories.info. Never give up, it can happen for you!!
Lifelove
Member
Posts: 58
Joined: Tue Nov 09, 2010 7:33 pm

Re: Lovenox is my next step

Post by Lifelove »

Thanks for the reply. (fingers crossed everything will be fine)
me-33 DH (34)
IVF1 & 2- 5/3/09 & 9/10 - chem
MTHFR - folbee
3- FET (12/17/09) BFP (7 wk m/c)
4- (4/14/10) BFN
5- (10/26/10) 3dt -ectopic
6- BFN
7- BFP - HCG 56.3 2nd 256
8-Fresh cancel
9-FET 11/28/11 BFP
http://www.thoughts.com/LittleStrawberry
angelaezra
Valued Contributor
Posts: 1180
Joined: Tue Oct 07, 2008 2:18 am
Location: Ohio

Re: Lovenox is my next step

Post by angelaezra »

Lynne – I have a clotting disorder called Lupus Antigen Clotting disorder and I am currently on baby ASA and Heparin daily. Lovenox is just a more expensive version of Heparin and with Lovenox you generally inject that once a day instead of twice as I do with Heparin. The studies have shown that the combination of baby ASA and Heparin/Lovenox works better to prevent clots than baby ASA alone. So that might be why your RE puts you on both. I am a nurse and have injected Heparin and Lovenox to numerous patients and I think it is just preference or formulary coverage as to why a doctor might pick one over the other. I hope this helps!

Angela
Image
1 miscarriage 2002 (nat)
1 ectopic pregnancy 2006 (nat)
1st IVF 10/08-BFP twins/misc-6 1/2 wks & stillbirth 21 wks
2nd FET 6/09-BFN
3rd IVF 2010-April-BFP - DD born 12/7/10

Lost Ashley Nicole Thomas at 21 weeks
Lifelove
Member
Posts: 58
Joined: Tue Nov 09, 2010 7:33 pm

Re: Lovenox is my next step

Post by Lifelove »

Thanks Angela it does help. :)
me-33 DH (34)
IVF1 & 2- 5/3/09 & 9/10 - chem
MTHFR - folbee
3- FET (12/17/09) BFP (7 wk m/c)
4- (4/14/10) BFN
5- (10/26/10) 3dt -ectopic
6- BFN
7- BFP - HCG 56.3 2nd 256
8-Fresh cancel
9-FET 11/28/11 BFP
http://www.thoughts.com/LittleStrawberry
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