Hello there,
After reading the thread on the NKC on this web site, after my first failed fresh and fet cycle I asked my doctor for the immunological testing. It came back with me positive for the NKC. Awful to say I was so relieved we had found something we could work on after not really having any straightforward diagnosis, I was sure the next fresh IVF would be the one. I was treated with Heparin injections and steroids, my progesterone two days after transfer shot up and I stopped my progesterone injections (as advised by the doctor) and just took the suppository two in the morning and night. I had three embryos, day three (i think they were 8 cells each) put back in. The only time I felt anything was two days after transfer with strong cramping in my lower abdomen. After that nothing. My pregnancy test not only came back negative but that it never even got going.
My husband and I live in Asia and have made the decision to move back to England to try to give ourselves a better chance. The doctor here admitted not really having immunology experience and would probably not do anything different. I still feel there are many more tests I could be having, ie testing the quality of the embryo which they don't do here, also I have not had my womb lining looked at.
I would love to hear from anyone also experiencing difficulty conceiving with an immunological problem, any success stories and also where they go. I am at a total loss, Bourn Hall would be the closest to me in Norfolk but they do not specialise in this, they recommended Dr Croft at the London Fertility Clinic and after reading on here I see the ARGC is highly recommended. Any advice and stories would be very much appreciated at this stage. You are all marvellous, if I hadn't found this web site i would never have got this far.
Thank you.
Foster
Any other people with Natural Killer Cells
Hi foster
Sorry you have been having a hard time. I have immune problems and was put on clexane ( blood thinner), dexamethasone ( steroids) and had IVIG. I did get pregnent with this but later M/C. Iwas told that due to my endo which they think is immune related ther would be no way that i could get pregnant without getting treatment for my NKC. Because i have endometriosis my body is constantly attacking any foreign bodies that enter so the embrios did not have a chance. I moved to ARGC and as i say i did get BFP but later lost it. I am about to start FET.
If you have any questions just ask.
Susan x
Sorry you have been having a hard time. I have immune problems and was put on clexane ( blood thinner), dexamethasone ( steroids) and had IVIG. I did get pregnent with this but later M/C. Iwas told that due to my endo which they think is immune related ther would be no way that i could get pregnant without getting treatment for my NKC. Because i have endometriosis my body is constantly attacking any foreign bodies that enter so the embrios did not have a chance. I moved to ARGC and as i say i did get BFP but later lost it. I am about to start FET.
If you have any questions just ask.
Susan x
ME 32 DH 31 Severe endo tubes blocked
3 ICSI 2 BFN 1 BFP then M/C
3 FET 2 BFN May 07 FET BFP sadly M/C 7 weeks.4th FET july[img]http://tickers.TickerFactory.com/ezt/d/4;10718;121/st/20070723/e/HCG+blood+test/dt/5/k/7a17/event.png[/img]
3 ICSI 2 BFN 1 BFP then M/C
3 FET 2 BFN May 07 FET BFP sadly M/C 7 weeks.4th FET july[img]http://tickers.TickerFactory.com/ezt/d/4;10718;121/st/20070723/e/HCG+blood+test/dt/5/k/7a17/event.png[/img]
Hi Susan
Thanks so much for sharing your story with me. I'm so sorry to hear about your m/cs and I really wish you well with your FET.
I think my blood thinner was called Prednisolone.
How did they diagnose your endo? What tests did they do?
Also I am nervous about an IVIG, what are the risks associated with this?
How did you find the ARGC staff and what prompted you to move there.
Sorry to ask so many questions but I get more sense of the boards than my doctor!
Foster
Thanks so much for sharing your story with me. I'm so sorry to hear about your m/cs and I really wish you well with your FET.
I think my blood thinner was called Prednisolone.
How did they diagnose your endo? What tests did they do?
Also I am nervous about an IVIG, what are the risks associated with this?
How did you find the ARGC staff and what prompted you to move there.
Sorry to ask so many questions but I get more sense of the boards than my doctor!
Foster
Foster
Hi foster
I was diagnosed with endo..... about 15 years ago via a laperoscopie and have had several laps in the past to treat my endo plus other meds.
Prednisolone is a steroid rather than a blood thinner i think as you can be on either Prednisolone or dexamethasone.
IVIG is what they coat your nks in and it is done introvenously for about 4-5 hours. it is very expensive though. There is alot of controversy over this med as lots of consultants dont believe in the immune theory but argc show the results.
If you like your hand held don't go to args the staff are nice but it is not done very privately. I was previously at barts and there you had a private meeting with the nurse ect but here you see the nurse in the main reception room ect but you do see the doctor privately. hoever the nurses do phone you every day to tell you how your results are and what level of meds to take so you can ask any personal questions then. The staff are very nice and do remember your name even thogh there are a lot of ladies there. I moved there as it was recommended to us by another couple. It is very expensive though but i feel it is more geared to you as an individual than other places. You have to have daily blood tests when you are on the stims and on second week of stims you will have to have twice daily blood tests.
Best of luck what you decide to do.
Susan x
I was diagnosed with endo..... about 15 years ago via a laperoscopie and have had several laps in the past to treat my endo plus other meds.
Prednisolone is a steroid rather than a blood thinner i think as you can be on either Prednisolone or dexamethasone.
IVIG is what they coat your nks in and it is done introvenously for about 4-5 hours. it is very expensive though. There is alot of controversy over this med as lots of consultants dont believe in the immune theory but argc show the results.
If you like your hand held don't go to args the staff are nice but it is not done very privately. I was previously at barts and there you had a private meeting with the nurse ect but here you see the nurse in the main reception room ect but you do see the doctor privately. hoever the nurses do phone you every day to tell you how your results are and what level of meds to take so you can ask any personal questions then. The staff are very nice and do remember your name even thogh there are a lot of ladies there. I moved there as it was recommended to us by another couple. It is very expensive though but i feel it is more geared to you as an individual than other places. You have to have daily blood tests when you are on the stims and on second week of stims you will have to have twice daily blood tests.
Best of luck what you decide to do.
Susan x
ME 32 DH 31 Severe endo tubes blocked
3 ICSI 2 BFN 1 BFP then M/C
3 FET 2 BFN May 07 FET BFP sadly M/C 7 weeks.4th FET july[img]http://tickers.TickerFactory.com/ezt/d/4;10718;121/st/20070723/e/HCG+blood+test/dt/5/k/7a17/event.png[/img]
3 ICSI 2 BFN 1 BFP then M/C
3 FET 2 BFN May 07 FET BFP sadly M/C 7 weeks.4th FET july[img]http://tickers.TickerFactory.com/ezt/d/4;10718;121/st/20070723/e/HCG+blood+test/dt/5/k/7a17/event.png[/img]
Hi Susan
Thanks for replying again. I am definitely leaning towards the ARGC, I don't really care at this stage about bedside manner, I just want a result. I am 38, have been TTC for 10 years and never been pregnant. I'd be happy to have the consultation in the middle of the high street if that is what it took for a good outcome!
I had no idea the IVIG took so long but I am worried that it is the equivalent of a blood transfusion with all the risks associated with it. I hope you didn't feel too bad afterwards.
Good luck with your FET, I have a good feeling for you on this one.
Foster
Thanks for replying again. I am definitely leaning towards the ARGC, I don't really care at this stage about bedside manner, I just want a result. I am 38, have been TTC for 10 years and never been pregnant. I'd be happy to have the consultation in the middle of the high street if that is what it took for a good outcome!
I had no idea the IVIG took so long but I am worried that it is the equivalent of a blood transfusion with all the risks associated with it. I hope you didn't feel too bad afterwards.
Good luck with your FET, I have a good feeling for you on this one.
Foster
Foster