Hi,
I am curious to see if anyone has experienced a mc after IVF? I had my transfer two weeks ago, but started yesterday, with blood clotts, cramps and negative preg test. I plan to take another test tomorrow.. I guess that I don't want to give up hope and keep my spirits up. I have noone really to talk to as I have not told anyone due to my age (43) and privacy.
Anyhow, I will try again this summer and have been told by my dr. that I have a good ovarian response. Any suggestions on trying after failed ivf? How about any health issues that I should be worried about? I had fibroids removed during egg retrieval.. any experience in this department?
Good luck to all,
Ann
Miscarriage after IVF
Hi Ann.
I'm so sorry to hear of your miscarriage. It's such a rough time, but you sound like you're doing well and keeping things in perspective.
I too had a m/c after IVF. Mine was caused by 'trisomy' - an extra 14 chromosome, most likely caused by abnormal meiosis of my egg. I have read where 50% or more of eggs for women over 38 are chromosomally abnormal. Unfortunately, this continues to get worse over time.
The fantastic news is that you are a good responder and were able to get pregnant, so to look on the bright side of a really challenging time, you've accomplished a lot.
There is a procedure called "PGD" (preimplantation genetic detection) where your embryo's are tested before ET for a number of chromosomal abnormalities (not all). Since you're a good responder, maybe that's an option (btw - it usually costs more.) There's another, even more, specific embryo testing called "CGH" (comparative genomic hybridization) that tests even more chromosomes leading to even more accurate embryo selection. This is only available from one RE clinic in the US right now. Anyway, with either of these, the RE can avoid tranferring any embryo's that are abnormal, since those will likely lead to eventual m/c. You might talk with your doctor about these options.
In terms of how to avoid this....it's all a matter of getting good eggs. Protocol during stim's impact egg quality, according to many REs. Some use bcp's prior and/or estrogen prior to minimize the impact of androgens, which can impact egg quality. Most REs don't put much faith in the 'non medical' approaches to improving egg quality (herbal supplements, vitamins, diet, stress-reduction, toxin avoidance such as alcohol & caffeine) but I say, why not try it. If you're spending this much on IVF, why not try everything possible to improve egg quality? Just my thoughts, though, so I'd again hope your RE can offer you some good advice.
Good luck, hope this helps, and again, very sorry for your m/c. I wish you the best of luck in your next cycle and hope it's successful for you.
I'm so sorry to hear of your miscarriage. It's such a rough time, but you sound like you're doing well and keeping things in perspective.
I too had a m/c after IVF. Mine was caused by 'trisomy' - an extra 14 chromosome, most likely caused by abnormal meiosis of my egg. I have read where 50% or more of eggs for women over 38 are chromosomally abnormal. Unfortunately, this continues to get worse over time.
The fantastic news is that you are a good responder and were able to get pregnant, so to look on the bright side of a really challenging time, you've accomplished a lot.
There is a procedure called "PGD" (preimplantation genetic detection) where your embryo's are tested before ET for a number of chromosomal abnormalities (not all). Since you're a good responder, maybe that's an option (btw - it usually costs more.) There's another, even more, specific embryo testing called "CGH" (comparative genomic hybridization) that tests even more chromosomes leading to even more accurate embryo selection. This is only available from one RE clinic in the US right now. Anyway, with either of these, the RE can avoid tranferring any embryo's that are abnormal, since those will likely lead to eventual m/c. You might talk with your doctor about these options.
In terms of how to avoid this....it's all a matter of getting good eggs. Protocol during stim's impact egg quality, according to many REs. Some use bcp's prior and/or estrogen prior to minimize the impact of androgens, which can impact egg quality. Most REs don't put much faith in the 'non medical' approaches to improving egg quality (herbal supplements, vitamins, diet, stress-reduction, toxin avoidance such as alcohol & caffeine) but I say, why not try it. If you're spending this much on IVF, why not try everything possible to improve egg quality? Just my thoughts, though, so I'd again hope your RE can offer you some good advice.
Good luck, hope this helps, and again, very sorry for your m/c. I wish you the best of luck in your next cycle and hope it's successful for you.
About 30% of positive pregnancies are lost after IVF. This may be similar to the natural rate in patients of similar age, perhaps. But in natural pregnancies, nobody is monitoring their early hCG levels, so the many very early missed pregnancies are usually not noticed. Maybe a period was a few days late.
Given the negative pregnancy test, was this really a miscarriage?
Given the negative pregnancy test, was this really a miscarriage?
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ann argent
- Newbie
- Posts: 8
- Joined: Sun Feb 25, 2007 2:48 am
MC after ivf
Thank you for your information. I will look into these other areas. My dr. told me today that he believes it was due to chromosomal abnormalities, but his agency does not do pre-genetic testing. I asked for this option, but in Argentina it is not a common practice. Also, tomorrow, I will do the HCG test to determine if I was indeed pregnant or just had the symptoms.. I don't know. It has been very difficult for me as I have spent so many years planning this and preparing. But I will keep my spirits up and keep hoping that the next cycle will be successful. I wonder if my fibroid that was aspirated during retrieval had an impact on the whole process? Also, they were able to retrieve three eggs, and two did take (one was apparently better than the other). Well, thanks for listening.. I don't have anyone to share this sorrow with and I have been down all weekend. On top of everything, I am vegetarian and last night I had salmon, told the waitress that I get ill when I get meat proteins and she still serves me bacon underneath my salmon. I got so sick last night and on top of all the cramps, bleeding -- this is all I needed. Hopefully won't lead to another fibroid (meat proteins as all meat and chicken proteins cause my cycle to go into immediate bleedings and changes). So, this weekend has been a very trying one for me and I can't not seem to get motivated to get over this grief... in silence.
Thanks for listening
Ann
Thanks for listening
Ann