We need help - Did anyone had same experience ?

tony22 · Post by **tony22** » Sun Jan 27, 2008 9:32 pm

Hi Justin,

I appreciate the posts and the information. I will write to Dr. Winston as suggested. You are a gem of a person and its wonderful to have folks like you on this group. It keeps our hopes high. We decided we are not going ahead with second round until we have all the facts clear and have taken 2-3 expert opinions. I have actually gone ahead and scheduled an appointment with one of the best experts in our area that came highly recommended and I and my wife thought even if they are not in our insurance network, it might be worth the spending. I am hopeful we will find something as we share the facts of the case. I will also send a email to Dr. Winston in UK and will attach results of PGD for him for his review with the hope that he would respond - may be very briefly. Thanks again for your help and guidence.

Regards
Tony

sassynlv · Post by **sassynlv** » Sun Jan 27, 2008 10:13 pm

Tony--
My dh and I had the same thing happen with our first IVF a few years ago. We do ICSI due to some MFI. My dh is a biogenetics nerd and REALLY wanted to do PGD. On our #1 IVF we only had 4 fertilize... and all were shown by PGD to be complex chromosomally abnormal, and they all stopped growing by day 3. So I understand the disappointment and frustration.

Since that time, we have had a few embryos grow to blast (using 2 different med protocols). We have chosen not to repeat the PGD as recent reports and studies have shown it (in my opinion, and in the opinion of my RE) to be much less reliable and helpful than perhaps once thought-- at least when done for aneuploidy. We have, over three cycles, collected 32 ferts and will be thawing them out next week, but will not be doing PGD. We will be just watching to see which grow to blast. Our RE at one point did give us the option of using half donor sperm and half of dh's sperm in an attempt to determine where the issue may be and/or to use the embryos with donor sperm if they showed better development than those fertilized with dh's sperm. We declined because we would choose to adopt instead of using donors. But that is one option that you mentioned had been suggested to you and may be worth pursuing.

We were once given the names of two specialists in LA who are equipped to do more advanced sperm analysis. We eventually chose not to meet with them. I will attempt to find their names (although they might be the specialists you have already mentioned).

Good luck on making your decisions. IVF presents us with difficult choices, especially because whatever we choose has (often significant) financial consequences. I understand the frustration associated with having such poor PGD results and not being able to determine the origin so that it could be "fixed" for next time. I hope you find some information to help you in the decision process. Feel free to PM me.

Wishing you and your wife the best,

Sassy

TammyS · Post by **TammyS** » Sun Jan 27, 2008 10:57 pm

Tony....you can email my doc... Dr Goldfarb. He is with the Cleveland Clinic and was the first doctor in Ohio to have a baby born by IVF in 1983. He does PGD. His clinic is one of the only ones in the region who work with PGD. He reads his emails...and will get back to you...even though the email goes to this company first and then to him...(which they are in the works of correcting the problem)...so it may take up to 2 weeks to get an answer. I googled... Cleveland Clinic Dr Goldfarb...and emailed through "locateadoc"...there is other ways to email or contact him as well that you can also try. I found this while googling "Cleveland Clinic ICSI PGD" ........this is just part of the article:

Preimplantation genetic diagnosis (PGD). In 2002, the Cleveland Clinic IVF program launched its PGD program and is one of the only clinics in the region offering this technology. PGD involves removing a single cell from a developing embryo at the eight-cell stage. The cell is then analyzed and embryos with normal chromosome content are selected for transfer to the woman's uterus. For patients with sex-linked diseases or single gene disorders, genetic screening at the preimplantation embryo stage is a powerful technique. In these patients, IVF coupled with embryo screening can greatly reduce the risk of offspring being affected by the disease.

Good Luck ...I hope this helps.

goosemis · Post by **goosemis** » Mon Jan 28, 2008 7:16 pm

Tony - there is an ad at the top of this site for www.fertility-docs.com. I clicked on it and they seem to have a lot of info about PGD and sperm testing. Hope this helps!

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:42 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:44 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

JustinesBaby · Post by **JustinesBaby** » Mon Jan 28, 2008 8:47 pm

We need help - Did anyone had same experience ?

Thank You

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