Yes know allot about it....She should talk to her RE about having her see a Rheumotologist if he suspects auto immine issues, A rheumatologist is a dr that sepcializes in auto-immmune and things lke that, and with that can be thororoughly checked out for auto immune issues. I would also recommend talking with a Reproductive Immulogist to run a full blood panel.
http://repro-med.net/
http://repro-med.net/info/cat.php
My SIL just had a large panel of tests done because she had perfect blasts put back in her twice and had bighted ovum twice which is uncomon.
She tested ANA positive, with Methylenetetrahydrofolate reductase (MTHFR)
I have tested ANA positive with speckled pattern, Methylenetetrahydrofolate reductase (MTHFR) and a host of other stuff
I have both and RE and a Rheumotologist where my bloodwork is monitered closey because of my history with CTD and m/c.
Good Luck....I highly recommend a specialist