All & Ghost - Egg Quality/FET/Quantity ?????'s

[katieb1231]

Hi All & Ghost - I have a question - I am trying to understand the probability of a FET transfer taking - I have six frosties - they are as follows: 3-5BB, 2-4BB & 1-6BC - I am a little disappointed they are not better quality but I have heard that some women going through a FET opt to transfer in 3 so that it ups there chances of having 1 or 2 healthy babies - so now I am torn should I go for it and put in 3? OR Should I stick with original plan of only transferring two? Last time they transferred two they made & educated guess & said that the probability that both of them took was high so now I am worried about transferring three. Last cycle we transferred two had a BFP with first beta of 820 17dpo & second beta 5221 20dpo & then miscarriage at 5 weeks.

I am not sure about the quality of the eggs as well - anyone got any thoughts on that too? I guess my clinic uses a regular scale on grading (the same that most clinics use)

I want my best case scenario & am hoping for a BFP that sticks this time so any advice you all can give me I would greatly appreciate it. I don't know if I have the energy to go though this tons of times. You ladies are all so knowledgeable & I respect your opinions & advice so greatly.

Thanks! Katie

[LYD10]

that's a tough one! in my fresh cycle i transferred 2 and it didnt work. so for the frozen they transferred 3 and one worked. so we got more aggressive for the 2nd time. they told me that the chances of triplets are very low - less than 5%. would you be OK twins?

[katieb1231]

Yes we would be ok with two - with this past cycle we really wrapped our arms around having two (we have a two year old) and decided we are ok with it. I just worry that putting three in could cause a miscarriage because of too many in there??? Also I am concerned about my egg quality - my clinic says they are extremely conservative & grading & they very rarely get excellent quality eggs with a grading of 5AA or 6AA so mine they are extremely optimistic about - but they were optimistic the first time too - so I am confused?

[LYD10]

Yes we would be ok with two - with this past cycle we really wrapped our arms around having two (we have a two year old) and decided we are ok with it. I just worry that putting three in could cause a miscarriage because of too many in there??? Also I am concerned about my egg quality - my clinic says they are extremely conservative & grading & they very rarely get excellent quality eggs with a grading of 5AA or 6AA so mine they are extremely optimistic about - but they were optimistic the first time too - so I am confused?

So 5 and 6 - does that refer to the cell count? Is that a 5 cell embryo and a 6 cell embryo at day 3?

[katieb1231]

No they grade as follows -

The number refers to how expanded it is 5 being best & 6 being hatched
The first letter refers to the inner cell mass - A is best
The second letter refers to Trophectoderm - A is best

All of them are 5 day hatching blastocysts except the very last one which is a 6 day hatched blastocyst.

Thanks for the advice!!!!

[LYD10]

No they grade as follows -

The number refers to how expanded it is 5 being best & 6 being hatched
The first letter refers to the inner cell mass - A is best
The second letter refers to Trophectoderm - A is best

All of them are 5 day hatching blastocysts except the very last one which is a 6 day hatched blastocyst.

Thanks for the advice!!!!

Oh - ok - i havent had experience with 5 day blasts. mine were 3 day embryos last time. So - i cant be of much use - except to wish you good luck! what does the doc say at this point?

[katieb1231]

Yeah I don't know either - I am a little lost to say the least - but he has not said yet whether he would recommend two or three - we are waiting for him to answer that question. Thanks for the info - I am really leaning towards three so we have a better chance but freaked out about having triplets

[LYD10]

Yeah I don't know either - I am a little lost to say the least - but he has not said yet whether he would recommend two or three - we are waiting for him to answer that question. Thanks for the info - I am really leaning towards three so we have a better chance but freaked out about having triplets

when i put in my three day 3 embryos they only gave me a 5% chance of triplets

[anacris]

Katie, deciding how many to transfer is a very hard decision I think, you want it to work but at the same time you don't want to put your babies at risk with a high multiple pregnancy. I guess every clinics success rates with frozen are different I think in some the success rate is almost the same as the fresh, at my clinic the success rates are less with frozen. I had a fresh cycle, transferred two blasts and both took, for my second cycle that was a FET RE suggested 3, but I was too afraid of the risks of triplets and only accepted to transfer two, it resulted on a chemical pregnancy. So on my second FET I accepted the suggestion and transferred 3, I am now pregnant with one baby. At my clinic most of the women with FET end having one baby, but yes there is a chance of having triplets. For me the difference between a fresh and a frozen was huge, with fresh 2 out of 2 implanted versus 1 out of 5 (in two cycles) with FET. Do not remember the grading exactly but they were good quality blasts, not perfect but good.
This is my case and I guess everyone is different, I know is such a difficult decision.
Hugs and I am praying for a BFP and a healthy pregnancy for you katie,
Ana

[katieb1231]

Well the RE just told me he would highly discourage me from transferring three since the risk of triplets is between 5-10% and when transferring three the risk of twins jumps to 50%. I am still not sure what I will do I do not think my embryos are that high quality that they all take - but I am still just so confused by the whole process or what the egg quality truly is etc...... UGH

[Ghost]

Hi All & Ghost - I have a question - I am trying to understand the probability of a FET transfer taking - I have six frosties - they are as follows: 3-5BB, 2-4BB & 1-6BC - I am a little disappointed they are not better quality but I have heard that some women going through a FET opt to transfer in 3 so that it ups there chances of having 1 or 2 healthy babies - so now I am torn should I go for it and put in 3? OR Should I stick with original plan of only transferring two? Last time they transferred two they made & educated guess & said that the probability that both of them took was high so now I am worried about transferring three. Last cycle we transferred two had a BFP with first beta of 820 17dpo & second beta 5221 20dpo & then miscarriage at 5 weeks.

I am not sure about the quality of the eggs as well - anyone got any thoughts on that too? I guess my clinic uses a regular scale on grading (the same that most clinics use)

I want my best case scenario & am hoping for a BFP that sticks this time so any advice you all can give me I would greatly appreciate it. I don't know if I have the energy to go though this tons of times. You ladies are all so knowledgeable & I respect your opinions & advice so greatly.

Thanks! Katie

This is not medical advice, this is just what I would do.

It sounds like you have some so-so embryos, which is pretty typical, but somewhat unusual that they were frozen. So-so embryos tend to not do so well after thaw. Your clinic probably has some statistics for what implantation rate you might expect with your quality of embryos and your age group. If it's near 10% per transferred embryo, I just might transfer 3. If it's close to 30%, I would transfer no more than 2, and seriously consider transferring just one embryo. If it's 40% or higher, I would definitely just transfer one embryo. That reflects how I feel about the risk of multiples. You may feel differently and arrive at a different answer.

[katieb1231]

Ghost - I just heard from the RE and he stated that my embryos by the standards of their clinic are extremely good - they only assign a excellent rating to those that truly are excellent and that those are in less than 1% of all retrieved. He stated that mine are 5 day hatching blastocysts and that the 3 that are 5BB are some of the top ones they have seen in the clinic this year -the others they have seen have been either 5AB or 5BA. So with that being said I will transfer two & hope for two but be elated with one The percentage is between 40 & 50% for a pregnancy with live birth to occur with the quality of eggs I have. Each clinic I guess is different with how they grade & what percentage they give you.

I still am a bit confused but I am set on transferring two now I definitely don't want to have triplets & the RE seems concerned that with the quality I have that is a definite possibility. Who knows???? But I appreciate all your replies I quit drinking with all this IVF stuff just to give myself the extra edge but geez with all of this I think I need a drink!!!!!!!!!!!!!!!!!

[Ghost]

Each clinic I guess is different with how they grade & what percentage they give you.

Definitely true.

Best of luck.