FET August Cycle Buddies

Discussion forum for those particularly interested in IVF and embryo transfer including frozen embryo transfer.
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PMApsy
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FET August Cycle Buddies

Post by PMApsy »

Hi guys!

Don't know why, I just thought I'd check if anyone is doing an FET in August, just like me. I don't mean to exclude anyone, there's already an August-Sept. cycle buddies list. It's just that IVF and FET cycles are very different, and experienced differently.

So if you want to come for a chat, I'd be glad to make your acquaintance! :D

My name is Sophie, I live in Montreal and I work as a psychologist with cancer patients. You'll see in my profile that this is my 4th attempt. Wow, already! I'm still very calm about the process right now; I just miss chatting with fellow IVF/FETers! Nothing much is happening treatment-wise. I'm sniffing Suprefact 5 times a day, and I'm taking baby aspirin. Waiting for AF to show up, then I'll also take Estrace and antibiotics for 7 days. I'll have a u/s 14 days later, hence why I estimate FET for mid-August.

My clinic has amazing success rates now for FET; they changed their protocol around a year ago. The results keep getting better and better it seems. Everything is looking good, I'm keeping everything crossed while trying to keep conservative hopes and, above all, let go.

Have a good day! :)

Sophie
1st and 2nd IVF = BFN 1st FET BFP! m/c at 7 weeks. 2nd FET BFP! 3rd FET BFN
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kerpupples
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Post by kerpupples »

Hi Sophie! I'm not sure if you remember me but we had miscarriages right around the same time in March. :(

My very first AF after the MC didn't show up until July 10th! I started Vivelle patches that day and am set for a FET on Friday the 1st.

How has the estrogen been affecting you so far? I've been having some nausea and dizziness since the dosage has been upped. And I get to start the PIO shots again tomorrow. Yippee.

Amy
Amy
Me: 39 DH: 41 Male Factor
3yo DD from FET
IVF PGD clinical trial, FET Jan 2012 Beta 1/14 447, Beta 1/16 1161 U/S 1/30 it's twins!
Graham and Audrey born 9/5/12. 37w4d, no NICU time!
kimmysq
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Post by kimmysq »

Hi:
I am going through at FET on Wed, July 30th. Sophie, I would love to know your RE's meds protocol. My Re's success rates for FET are lower than the national average...I considered moving my frosties, but decided to stay and just see....
Can you share with me your med protocol, especially for transfer day and leading up to beta.
I am transferring 3 day frosties. I asked my RE if they could culture them to blasts, but they don't reccomend it...bummer

Either way, I am so excited for transfer day!!!
GL
Kim
FET July 30th transferred 4 embies.
beta 8/11 (12dp3dt) 332
beta #2: 8/13: (14dp3dt) 888
beta #3 8/17: (19dp3dt) 11,124
1st u/s: 8/27 6wks 3 dys.. TWINS!!
PMApsy
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Post by PMApsy »

Hi Amy!

Of course I remember you! It's great to see you again. I, too, had weird cycles after my miscarriage, although it was the exact opposite of you. They had trouble stopping the bleeding, though I suspect my tubal condition was responsible for this. Anyway.

Happy to hear that you're giving FET a go real soon!!! :D I'm not due to take estrogen until AF shows up. Last time, though, it had a major side effect that was not great at all... I, too, tend to have strong gastro-intestinal symptoms on meds that are high in estrogen. Strangely, it wasn't so bad at all with the pure estrogen in Estrace. However, I had a rare side effect, which is elevated libido. Let me tell you, it wasn't funny... imagine being in your 2ww, in that state (and we're talking scratching the paint off the walls here), without any possibility to calm down your hormones! Too bad they keep you on PIO... it's for a good cause sweetie. Let's become preggers again and sail through pregnancy together all the way this time! *HUGS* I hope the nausea will subside...

Hi Kim, nice to meet you! awww ,your frosties are coming back home real soon!!!! Best of luck my dear! Keeping everything crossed for you! :D My clinic's protocol is as follows:

Day 1 : call the clinic and let them know you want to do an FET protocol.
Day 21: start taking Suprefact and baby aspirin. Suprefact is deemed better than, say, Lupron, because downregging is as effective but less harsh on the hormonal system. Sucess rates went crazy when they made the switch, apparently.
Day 1: call the clinic to let them know AF started. Start taking Estrace (1mg twice a day I think) and Vibramycin (ouch, spelling), an antibiotic. Now the clinic prescribes 7 days of antibiotics for both the father and the mother (IVF fresh cycles), and only to mummies for FET. Although we do our best to keep the procedures sterile, sperm can be contaminated during ejaculation, eggs may be contaminated during ER and the embryos can be contaminated during transfer. Antibiotics provide a safer environment (vagina/urethra), and apparently it has an impact on success rates.
Day 2-14: Estrace doses are gradually increased to 6mg a day (three 2mg doses).
Day 14: ultrasound to check lining. If it's around 11mm, it's a go. Suprefact intake stops.
Day 15: Start taking Prometrium (progesterone pessaries; better than PIO according to my doctor because it provides a steadier dose over a 24-hour period compared to PIO, one big dose that slowly decreases over 24 hours). 2 pearls three times a day. Embies are thawed.
Day 16: embryologist calls to tell you how many embies survived; transfer is done in the afternoon. Assisted hatching is done automaticaly on each embie as a courtesy. The clinic has us rest in bed for 1 hour, and then we leave the clinic. Bed rest is absolutely not recommended after that (it's bad for circulation and can actually lower implantation rates).
Day 16-29: continue taking progesterone, estrace 6mg per day, and baby aspirin. Beta is taken on day 29. If positive, baby aspirin is stopped but the other two meds are continued.

Hope that helps... don't hesitate if you have other questions. Don't worry about the age of your frosties. My clinic used to offer blast transfers before, but they don't do it anymore, not typically. They said that the best place for an embryo to survive is the womb, period. The main reason why some embryologists insist on culturing the embies to blast stage is they want to discriminate which embies are the strongest. My embryologist told me that, with experience, they know right away which embies are the strongest, and they no longer have reasons to culture them to blast. So don't worry about that. Studies show it doesn't make a difference in the end. It's more important to choose the embies wisely.

Okay, time to say goodnight! Take care ladies, and good luck!!!! :D

Sophie xxxox
1st and 2nd IVF = BFN 1st FET BFP! m/c at 7 weeks. 2nd FET BFP! 3rd FET BFN
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kimmysq
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Post by kimmysq »

Sophie:
Thank you so much for the detailed report of your FET!! It helped me so much, and I have a very big question for my RE. Why do they reduce my estrogen pills to once per day three days before transfer??? I did it last cycle and got a BFN. About 6 days after a 3dt, I had a terrible headache...all I could think about is that my hormones were way out of whack....I just knew something wasn't right.
Hopefully, I will get answers on this tomorrow. If I read your email correctly, you stay on 6mg of Estrace after transfer...correct???

So excited for my transfer on Wednesday! yeah, hope my embies survive the thaw well.
Baby dust,
Kim
FET July 30th transferred 4 embies.
beta 8/11 (12dp3dt) 332
beta #2: 8/13: (14dp3dt) 888
beta #3 8/17: (19dp3dt) 11,124
1st u/s: 8/27 6wks 3 dys.. TWINS!!
PMApsy
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Post by PMApsy »

Hi Kim!

Glad I could help! But you know, for future reference, the medication surrounding transfer day is important, but so are the meds taken during the surrounding weeks!!! For example, the Suprefact-Estrace combination really help to build a nice lining. Not just thick; high quality.

You read correctly. We continue taking estrace 6mg daily (three doses of 2mg) about a week before transfer, and all the way through the first trimester. It never stops. Even when I had severe bleeding and was at high risk for miscarriage, they had me stick to the estrace pills. I heard wonders about estrace, and apparently even in IVF fresh cycles, when you take estrace during your 2ww you have increased chances. Some clinics only prescribed this to older women who struggled with hormonal factors. But now, my clinic has made the switch for everyone having embryo transfer, fresh or frozen.

I hope your doctor will have a nice attitude with all this... and I really hope you'll get a nice BFP! Embies are coming home soon!!! When will you know how many embies survived? How many do you thaw?

Talk to you soon!

Sophie :)
1st and 2nd IVF = BFN 1st FET BFP! m/c at 7 weeks. 2nd FET BFP! 3rd FET BFN
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kimmysq
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Post by kimmysq »

Hi Sophie:
Well, went to the RE office this mornig and they have still want me to take only 2mg of Estrace today. I think I might push it to 2 pills per day (4mg).
My lining was 8.7, which they say is fine. But when I did get pg from a IVF cycle my lining was 12. So, yes, now I am freaking out about my lining. Ugh, wish I had your RE's protocol. Told them I would be happy to cancel is they didn't like my lining, but they said it is fine...we will see.
Well, let's see how many embies make the thaw tomorrow.

Baby dust,
Kim
p.s. what clinic do you go to and where is it?? Mine is in Ca.
FET July 30th transferred 4 embies.
beta 8/11 (12dp3dt) 332
beta #2: 8/13: (14dp3dt) 888
beta #3 8/17: (19dp3dt) 11,124
1st u/s: 8/27 6wks 3 dys.. TWINS!!
PMApsy
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Location: Montreal

Post by PMApsy »

Hi Kim,

I live in Montreal, and my clinic is called Procrea. Apparently, the McGill clinic has amazing success rates too. My clinic's new protocol originates from another clinic in Calgary, which is supposed to have the highest success rates in Canada (around 60% u/s confirmed pregnancies). Given that you live in Ca, I guess it's much too far... :(

I wouldn't fret too much about your lining, sweetie. I think the ideal lining is 1cm. You're not very far from that, and think about it... your lining will continue to thicken today and tomorrow. You might even have another day after that, given that your embies might not implant right away. It will have reached that perfect 1cm by them. Have you started taking progesterone? That boosts the lining as well. Plus it's not only a matter of thickness, but layers. My gyn told me that when you see the three layers (they have names, but I don't remember) then everything is just perfect. Maybe your doctor saw that and that's why he's reassured. Everything is looking good dear.

As for the meds, well.. it's a toughie. How much estrogen were you taking yesterday? When do they want you to drop to 2mg? I can't advise to change your meds' dosage without your doctor's consent... although 2 more mgs a day is a negligible difference, so the risk is not that big. Either way, I'm sorry your doctor doesn,t have more flexibility. What reason did he/she give you?

And Amy, how are you doing sweetie? Big day is comiiiiiing! :D

As for me, I had a super hectic day yesterday. Our handyman (we've bought a new house and redone the whole interior) is finishing our kitchen and he told us only yesterday that it was better to have the walls painted before the backsplash is installed... and today is his last day! So yesterday I litterally escaped from work (boss is away, not a soul noticed) and I spent a couple of hours sanding the ceiling and walls (plastering), then priming everything with DH, then two coats on the ceiling and two coats on the walls! We finished around 10:30pm (9 hours of work with almost no breaks!), but we have a good-looking kitchen, let me tell you!

And in the evening, surprise! AF showed up! She showed up earlier than she did on my last cycle (10 days of Suprefact instead of 7 this time). I called the clinic and started taking estrace and antibiotics today. U/s is planned on the 11th, which means transfer should happen on the 13th. Whoa, this is faster than expected!!!! Gotta change my ticker! :D it's an exciting milestone! :D

Okay, gotta run to the drugstore for my meds. But take care ladies, and you're in my thoughts!

Sophie xxox
1st and 2nd IVF = BFN 1st FET BFP! m/c at 7 weeks. 2nd FET BFP! 3rd FET BFN
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PMApsy
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Post by PMApsy »

Hi Kim!

I just wanted to tell you good luck for your transfer today! :) Little embies, find a nice spot in there and stick to your mummy! You're in for a loooong nap!!!

See you soon I hope! :D

Sophie
1st and 2nd IVF = BFN 1st FET BFP! m/c at 7 weeks. 2nd FET BFP! 3rd FET BFN
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kimmysq
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Post by kimmysq »

Hi:
So happy that your AF started early and you have your FET date. yeah!!

4 out of 8 embies survived the thaw yesterday. 1 8 cell, 1 6 cell and 2-4 cell. Yeah! Transfer went well and I spent the day in bed. RE said I didn't have too, but it made me feel better.
I cancelled my AP appt....for some reason they were stressing me out.

I am officially PUPO. Yeah!
Kim
FET July 30th transferred 4 embies.
beta 8/11 (12dp3dt) 332
beta #2: 8/13: (14dp3dt) 888
beta #3 8/17: (19dp3dt) 11,124
1st u/s: 8/27 6wks 3 dys.. TWINS!!
kerpupples
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Post by kerpupples »

Congrats Kimmy, sounds like things went well for you!

Sophie, very cool that AF came early. Not too long for you now!

I'm just cruising along until tomorrow morning. I have no plans for bedrest (NOT in my nature and my RE doesn't require it) but I will be taking it easy and will let you all know how it went!
Amy
Me: 39 DH: 41 Male Factor
3yo DD from FET
IVF PGD clinical trial, FET Jan 2012 Beta 1/14 447, Beta 1/16 1161 U/S 1/30 it's twins!
Graham and Audrey born 9/5/12. 37w4d, no NICU time!
PMApsy
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Location: Montreal

Post by PMApsy »

Hello ladies!!

Kim,
I'm glad your FET went well! Whoa, many babies-to-be in there now! :D Welcome to the princess status! :D:D:D:D Let us know how you're doing during your 2ww! About the bedrest, though, make sure you move around a little bit at least once every hour or so. Strict bed rest is really bad for circulation, and other than clot issues, your uterus needs a good blood flow to help your embies stick.

kerpupples,

GOOD LUCK for tomorrow morning! You're almost there! :D Please let us know, I'll be checking for sure! I hear you on the bedrest dilemma. My clinic is against it, and I've read studies that show it makes no difference and can even lower your chances when it's too strict. But as Kim said, you must do what makes you feel better! Personally, I just take it really easy on the first day, I stop dancing, sports, I don't take super-hot baths, no nookie of course, I lead a normal otherwise. Over-analyzing what you can or cannot do, for want of feeling in control over what is uncontrollable at that point, creates such unneeded stress!

Okay, editorial done! Must take a short walk to chinatown and get that pastry I've been craving this past hour! Take care ladies!!!

Sophie xxox
1st and 2nd IVF = BFN 1st FET BFP! m/c at 7 weeks. 2nd FET BFP! 3rd FET BFN
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shep181
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Post by shep181 »

Hello Ladies...Count me in!!!
I just had my FET this morning...transferred 2 5 day blasts.
I've been lurking the last few days to see if anyone was FET'ing around the same time and voila! Here you all are...

I live in NH, clinic in Massachusetts, but here was my protocol this time (same as last):

Varying doses of Estrogen after AF showed up, now on steady 2mg twice daily, and of course, the torture wouldn't be complete without the dreaded PIO shot, started a week ago.

Now it's just obsess and wait, wait and obsess... :lol:

They thawed 3 to get 2, and we are still blessed to have 3 on ice...all day 5's...

Kim and Amy, when are your betas?
Sophie, congrats on your date!!!!

Any thoughts on how to entertain ourselves on the dreaded 2ww????
Take Care,
Ericka
Me: 36 DH: 37
TTC: forever!
6 ICSI fresh and FET's, 2 chemical, rest BFN
IVF #7: Dec 09 BFP!!!!
Beta 1: 175 Beta 2: nasty case of OHSS
kimmysq
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Post by kimmysq »

kerpupples:
good luck tomorrow on your FET! My Re also doesn't require bedrest, but I just felt better lounging around yesterday. Emotionally tired, but so happy to have the embies where they belong!
How much estrace are you on after your ET?

Shep181: How exciting that you had 2 blasts transferred! You have a great chance of success! I am also on the dreaded PIO...twice/day 1cc each time. What is your dose?
I see you are taking Estrace 2mg twice/day. I am only once, but would feel better taking two.

Sophie:
Thanks for all the great advice. I love it!

My beta is 8/9. I POAS last time and it made me so sad as I kept seeing -negative. We shall see this time. What are all of you doing?
My dh is taking me to the beach for the next couple of days. Should be fun and keep me distracted.

Baby dust,
Kim
FET July 30th transferred 4 embies.
beta 8/11 (12dp3dt) 332
beta #2: 8/13: (14dp3dt) 888
beta #3 8/17: (19dp3dt) 11,124
1st u/s: 8/27 6wks 3 dys.. TWINS!!
shep181
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Posts: 87
Joined: Sun May 06, 2007 9:26 pm

Post by shep181 »

Hi Kim,

I started a book...actually took a nap today...the next few days, just trying not to work. Last fresh cycle was cancelled due to OHSS, and I'm not convinced the ridiculous work stress I was under didn't contribute...

I am on 100mg PIO, just one daily. I can't imagine twice a day!!! The shot isn't bad, but having to get home every night at the same time is a challenge.

I have my HPT arsenal ready to go. I would like to tell myself that I will just wait, but I am a realist. I think I will try to wait til 7dpt before I start obsessing though.

Take care!
Ericka
Me: 36 DH: 37
TTC: forever!
6 ICSI fresh and FET's, 2 chemical, rest BFN
IVF #7: Dec 09 BFP!!!!
Beta 1: 175 Beta 2: nasty case of OHSS
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