Low Ovarian Reserve

Discussion group for all topics related to infertility including preparation for pregnancy, causes, investigation and treatment of infertility.
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LozzyLL
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Posts: 9
Joined: Tue Jul 13, 2004 7:27 pm

Low Ovarian Reserve

Post by LozzyLL »

Hi Everyone

Been reading through your messages, you guys are so brave and strong.
I went through my first cycle of IVF in March had 8 follicles, 5 fertilised 2 were implanted and 1 was frozen. Unfortunately it didn't work, totally devestated. So had a break, saved up, and decided to start again this month.
On day 7 test only had 2 follicles in left ovary none in right, my heart sunk they said they don't usually recommend going ahead with only 2, I know they are probably right but I don't know what to do, this might be my last chance and better to have tried rather than always think what if?

Has anyone else had a low folicle count one month but a higher one afterwards, they seem to think it won't get better only stay same or get worse, if this is right then I feel I must go for it even though they say it almost definitely won't work? How can it have reduced so much in such a short time?

Sorry just needed to get that off my chest and get some second opinions am I clutching at straws?

Kind regards
LozzyLL
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TERESAWANTBABY
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Posts: 131
Joined: Fri May 07, 2004 11:14 am
Location: Canada

Post by TERESAWANTBABY »

Hey Lozzy,
I never had this happen but can't get up the meds to increase the number of follicles ???

-Teresa :D
TTC 20 months
Me 28 Dh 31 low sperm count
IVM/ICSI 1st try
IVM (Invitro Maturation) Natural Cycle (no meds)
PREGNANT !!!
EDD March 21, 2005
Traci
Valued Contributor
Posts: 2176
Joined: Mon Jan 06, 2003 10:36 pm
Location: oxfordshire

Post by Traci »

LozzyLL
Hi , I am so sorry the first cycle didnt work for you , I have had exactly the same happen to me , they were thretening to cancell the cycle and I said no , anyway with some perswading they let me go another 2 days and still not any more so I asked seeing as my tubes are ok then lets not waist this cycle and turn it into IUI , anyway they said go 2 more days and they will check my eastrogen levels and if they were high enough to show egg activity then they would let me do IUI, ANYWAY when we went back after being on stimms 300iu for 12 days I had 3 good sized follis and they decided to go for ICSI again, the ec took place and I got 4 eggs and ended up with 3 fertilised and 2 grade A'S put back Unfortunately this ended in a Neg :cry: since then have resigned myself to the fact that my eggs wernt good enough and have had 2 further goes with two cycles with donor eggs but still neg , now I am not sure if it is egg quality ,I have FSH of 6.4 then 10.3 then 12.3 then 16.1 then 23.6 then after 2 months =9 goes of acupuncture I got a 3.6 Over the moon!!!! so on the 2nd of sept we have our consultant chat about the future so we will see .

Anyway

The moral of the story is DO NOT GIVE UP JUST GO FOR IT OR YOU WILL NEVER KNOW , PUSH THEM!!!!!!!! ITS YOUR BODY


Best of luck

Trace x
will be watching how you get on
DebraP
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Posts: 2784
Joined: Sun Nov 23, 2003 4:40 pm

Post by DebraP »

Hi Lozzy...I guess alot depends on where you're having tmt and how it's being paid for. If you've paid already/or this counts as a funded tmt, why not see this cycle though? what have you got to lose? I've not heard of this before, but if you're in the US I know they'll put back more than the maximum 2 they allow here in Europe, is it possible to have your frozen egg put back at the same time as the potential two you've got now? Does that sentence make sense?

Have they said why they think you're a low responder? like Teresa asked, will a last boost of meds help? I've had to increase my dose of Puregon to 300 both times in the last few days to get the numbers and sizes up.

Difficult choices but if you're committed to this cycle, I can understand why you'd not want to give up now.

hugs,
Debra.
Me: 44, DH: 31
Game Over.
Dates: Aug 02 - May 06
Tries: 5 fresh + 4 frozen.
Results: 1 daughter, 2 m/c, 1 ectopic.
LozzyLL
Newbie
Posts: 9
Joined: Tue Jul 13, 2004 7:27 pm

Post by LozzyLL »

Thanks all. Helps to have someone to talk to and know that you are not the only one going through this.

Teresa already on full 450 doseage so can't up it any more , tommorow is d'day taken my last lot of Puregon tonight so will find out tommorow if the 2 I have are big enough to continue if they're not then I guess we don't have to make that decision :o(

Trace What is IUI? Does the FSH levels relate to the number/quality of eggs my FSH levels were lower this time than they were the first time which is why I can't understand the low response especially as I am taking a higher dose of Puresgon than before? Acupuncture sounds interesting, if tommorow is bad news may be I could try that before heading down the donor egg road? Do you have to wait a long time for a donor? Hope you get good news on 2nd Sept. x

Debra I am in UK so they only do 2 at my clinic I think you can put the frozen one in as well as a new one, we'll see what they say tommorow.

Thanks for your support, If I can I am going to go for it however small a chance a least it's a chance. I could be that one in a million?!

Good luck to you all, and thanks again, will let you know how it goes.
LozzyLL x
Traci
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Joined: Mon Jan 06, 2003 10:36 pm
Location: oxfordshire

Post by Traci »

FSH and LH blood levels
Measurements of these hormones needs to be carried out at a particular time during the woman's menstrual cycle (usually between day 2-4 of menstruation) for the results to be valid. High FSH levels generally indicates diminished ovarian reserve while low FSH levels may indicate disorders of the pituitary or hypothalamus glands.

In the UK between 3 and 8 is a good FSH level

Hope this helps!

I was told that they always look at your highest reading of FSH because that is the true reading , the FSH will fluctuate every month Look at mine!!!!! At one time they were going to do a short Protocol where you dont downreg you just started stimms on day 3 so in effect you used the fsh that was in your body as well as the top up of stimms.
LozzyLL
Newbie
Posts: 9
Joined: Tue Jul 13, 2004 7:27 pm

Post by LozzyLL »

Bad news had the folicles measured this morning 2 at around 16.5 mm 1 at around 10mm. Phoned back this afternoon my bloods were down so don't recommend I continue with this cycle as nearly nil chance of anything happening, I still want to go ahead but everyone is saying it's not worth the risk.
May use the money it would have cost for the EC/ET to have some accupuncture sessions and have another try in a couple of months, may have a few more follicles then or am I clutching at straws?


Thanks for all your support

LozzyLL :cry:
DebraP
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Posts: 2784
Joined: Sun Nov 23, 2003 4:40 pm

Post by DebraP »

Lozzy, this is a really tough call for you and DH. Is he letting you make the decision? what's his opinion? Not sure I understand the bloods reference but trust you know what it means. What's so sad is 16mm sounds really good to me. If the clinic are strongly recommending you don't go ahead, then maybe they know the odds and want to save you the heartache and crushed hopes. On the otherhand, if you need to see this go through, and the money isn't a major issue, can you decide to do it anyway?

If you don't, I think the idea of accupuncture sounds like a good one. Lots of girls on here have tried it and had positive experiences from its effects. I think they suggest at least a few months of it though, if not more.

Sorry you've got this difficult decision to make. How long do you have?
hugs
Debra.
Dagny
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Location: Redhill, Surrey

Post by Dagny »

Hi Lozzy

Welcome to the site. I am sorry you have had you treatment cancelled as your follicles haven't grown enough. It is so soul destroying. I remember having a panic about that happening to me and asking my consultant about it. He said it can happen that you get a good amount one time and the next hardly anything at all. There is no reason for it apart from your body combatting the drugs or that your FSH levels were not great for that cycle.

I hope you get to have a chance to talk it through with your doctor and see if he has got any solutions for future treatments.

Take care

Love Dagny xkx
Me 38 DH 40
1st 2nd & 4th IVF/ICSI -ve
3rd +ve DD Katelyn born @ 24wks & sadly died
5th +ve m/c 9wks
6th +ve Twins Sadly DD Leah stillborn @20wks and DS Kieran born @22wks but sadly died too
7th +ve - DD Chloë Mae born @38wks our precious miracle
Traci
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Posts: 2176
Joined: Mon Jan 06, 2003 10:36 pm
Location: oxfordshire

Post by Traci »

Lozzy
I am so sorry you must feel absolutly gutted , I know how I felt when this was happening to me , anyway I had acupuncture every week for 2 months and my FSH went down to 3.8 , not sure if this was a coinsidence cause they found 2 cysts on my ovaries. therefore I couldnt go for a cycle that month. then I had a donor come along so I went for that but will try again next year with my own eggs just to make sure.

Good luck with the acupuncture, by the way have you heard of the HSA cause if you join you could claim half your acupuncture back.
LozzyLL
Newbie
Posts: 9
Joined: Tue Jul 13, 2004 7:27 pm

Post by LozzyLL »

Thanks everyone, I only had a few hours to make the decsion as would have had to take my HCG injection (I hate that one!) at 10pm so after long discussions with DP who is absolutely fantastic and supports my decision 100% what ever it may be and parents etc we decided to cancel the treatment this was so hard but the odds seemed to go down every day, I don't really understand the blood thing either Debra but every time they do a scan they do a blood test and this should be high with something, some sort of hormone I would think (anyone know?) it ws rising all week but that day it had gone down which was another bad sign.

Not sure what I should be doing now no one from hospital has contacted me does my body just go back to normal and the follicles I have there just go with a normal period?

Any way trying to stay positive, going to talk to an acupunturist, going to loose some weight I was a little more than I was last time, get fit and do everything I can to help the next one, I hear that drinking lots of water is good for the treatment is that right? What's HSA Trace?

Take care everyone and wishing you lots of luck, you really deserve it, I'll keep an eye out to see how you are all doing.

Bye for now
LozzyLL xxx
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