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Risks and complications of IVF treatmentMultiple pregnancyIn the majority of patients, fewer than 20% of the embryos are implanted after embryo transfer to the uterus, so two or more embryos are usually replaced which results in high-order multiple pregnancies. The latest data from the USA (SART 2002) concerning multiple pregnancies showed that 32% of deliveries after in-vitro fertilization (IVF) were twins and 7% were triplets or more. In the United Kingdom (HFEA patient's guide 2002), 25% of deliveries after IVF were twins and 1.7% were triplets. It is important to note that in the United Kingdom, the maximum number of embryos to be replaced per cycle is three. In order to reduce the risk of multiple pregnancy, the HFEA in the United Kingdom (August 2001) has decided to reduce the number of embryos to be transferred from three to two. In exceptional circumstances a three eggs or embryos transfer may be performed. This will be case specific and indications might include clinical and laboratory criteria. Countries have different regulations and restrictions with regard to the number of embryos to be transferred.
Although the prospect of twin or triplets may seem attractive to some couples, high order of multiple pregnancies is associated with increased risks of maternal and fetal complications. In addition, multiple pregnancies place enormous strains for the parents including financial difficulties, emotional distress and physical exhaustion. Page:1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
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