Problems associated with ovarian stimulation by fertility drugs

There is no drug that is absolutely safe and completely free of side effects. The fertility drugs that stimulate ovulation are rarely associated with complications. There are potential problems, which may occur and include: side effects of fertility drugs, ovarian hyperstimulation syndrome (OHSS), multiple pregnancy, adnexal torsion (ovarian twisting) and the risk of ovarian cancer.

The committee on the safety of medicine in the UK has advised that no medical products using urine sourced in a country which has reported case(s) of variant form of human Creutzfeldt Jakob disease; this includes metrodine high purity (February 2004).

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